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| src-Family Kinases Protein-Tyrosine Kinases, src | src Kinases | src Tyrosine Kinases | src-Family Tyrosine Kinases | Kinases, src | Kinases, src Protein-Tyrosine | Kinases, src Tyrosine | Tyrosine Kinases, src | Tyrosine Kinases, src-Family | src Family Kinases A PROTEIN-TYROSINE KINASE family that was originally identified by homology to the Rous sarcoma virus ONCOGENE PROTEIN PP60(V-SRC). They interact with a variety of cell-surface receptors and participate in intracellular signal transduction pathways. Oncogenic forms of src-family kinases can occur through altered regulation or expression of the endogenous protein and by virally encoded src (v-src) genes. | |
| Protein-Tyrosine Kinase Tyrosine Protein Kinase | Tyrosine-Specific Protein Kinase | Tyrosine Kinase | Tyrosylprotein Kinase | Kinase, Protein-Tyrosine | Kinase, Tyrosine | Kinase, Tyrosine Protein | Kinase, Tyrosine-Specific Protein | Kinase, Tyrosylprotein An enzyme that catalyzes the phosphorylation of tyrosine residues in proteins with ATP or other nucleotides as phosphate donors. EC 2.7.1.112. | |
| Tyrosine Transaminase Tyrosine Aminotransferase | Aminotransferase, Tyrosine | Transaminase, Tyrosine An enzyme that catalyzes the conversion of L-TYROSINE and 2-oxoglutarate to 4-hydroxyphenylpyruvate and L-GLUTAMATE. It is a pyridoxal-phosphate protein. L-PHENYLALANINE is hydroxylated to L-tyrosine. The mitochondrial enzyme may be identical with ASPARTATE AMINOTRANSFERASES (EC 2.6.1.1.). Deficiency of this enzyme may cause type II Tyrosinemia (see TYROSINEMIAS). EC 2.6.1.5. | |
| Receptor Protein-Tyrosine Kinases Receptors, Protein-Tyrosine Kinase | Tyrosine Kinase Linked Receptors | Tyrosine Kinase Receptors | PTK Receptors | Protein-Tyrosine Kinase Receptor | Receptor Protein-Tyrosine Kinase | Kinase, Receptor Protein-Tyrosine | Receptors, PTK A class of cellular receptors that have an intrinsic PROTEIN-TYROSINE KINASE activity. | |
| Receptor, trkC NTRK3 Receptor | Neurotrophin 3 Receptor | Protein-Tyrosine Kinase TRKC | Receptor, Neurotrophic-Tyrosine-Kinase Type 3 | trkC Receptor | NTRK3 Protein | Neurotrophic Tyrosine-Kinase-Receptor Type 3 | trkC Protein | Protein Tyrosine Kinase TRKC A protein-tyrosine kinase receptor that is specific for NEUROTROPHIN 3. It is widely expressed in nervous tissue and may play a role in mediating the effects of NEUROTROPHIN 3 on the proliferation and differentiation of NEURONS. | |
| Protein-Tyrosine-Phosphatase PTPase | Phosphotyrosine Phosphatase | Tyrosine Phosphatase | Tyrosyl Phosphoprotein Phosphatase | PTPase 1B | Phosphotyrosyl Histone Phosphatase | Phosphotyrosyl Protein Phosphatase | Protein-Tyrosine Phosphatase | Phosphatase, Phosphotyrosine An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis. EC 3.1.3.48. | |
| Receptor, EphB2 EphB2 Receptor | Cek5 | DRT Gene Product | DRT Protein | Developmentally Regulated EPH-Related Tyrosine Kinase | EPHT3 Gene Product | EphB2 Protein | EphB2 Receptors | EphB2-Tyrosine Kinase | Nuk Protein | Sek3 Protein | EphB2 Tyrosine Kinase An eph family receptor found widely expressed in embryonic and adult tissues. High levels of EphB2 receptor are observed in growing AXONS and NERVE FIBERS. Several isoforms of the protein exist due to multiple alternative mRNA splicing. | |
| Tyrosine Decarboxylase Decarboxylase, Tyrosine A pyridoxal-phosphate protein that catalyzes the conversion of L-tyrosine to tyramine and carbon dioxide. The bacterial enzyme also acts on 3-hydroxytyrosine and, more slowly, on 3-hydroxyphenylalanine. (From Enzyme Nomenclature, 1992) EC 4.1.1.25. | |
| Tyrosine L-Tyrosine | Tyrosine, L-isomer | para-Tyrosine | L Tyrosine | Tyrosine, L isomer | para Tyrosine A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE, THYROID HORMONES, and melanin. | |
| Receptor, EphA2 Eck Gene Product | Eck Protein | EphA2 Protein | EphA2 Receptor | EphA2 Receptor Tyrosine Kinase | EphA2-Tyrosine Kinase | Epithelial Cell Kinase Protein | Mammary-Derived Tyrosine Kinase 2 | Myk-2 Protein | myk-2 Gene Product | Myk 2 Protein An Eph family receptor found abundantly in tissues of epithelial origin. It is expressed in a diverse array of tissues during embryonic development, suggesting that it may play a role in embryogenesis. In adult tissues high levels of the receptor are expressed in the LUNG; SKIN; SMALL INTESTINE and OVARY. | |
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