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Protein Kinase C
Calcium Phospholipid-Dependent Protein Kinase | Calcium-Activated Phospholipid-Dependent Kinase | PKC | Phospholipid-Sensitive Calcium-Dependent Protein Kinase | Protein Kinase M | Calcium Activated Phospholipid Dependent Kinase
An enzyme that phosphorylates proteins on serine or threonine residues in the presence of physiological concentrations of calcium and membrane phospholipids. The additional presence of diacylglycerols markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by phorbol esters and it is believed that protein kinase C is the receptor protein of tumor-promoting phorbol esters. |
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