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| Aromatase CYP19 | Cytochrome P-450 CYP19 | Cytochrome P-450(AROM) | Androstenedione Aromatase | CYP 19 | CYP19 Protein | Cytochrome P450 19 | Estrogen Synthase | Estrogen Synthetase | P450AROM | Aromatase, Androstenedione | Cytochrome P 450 CYP19 An enzyme that catalyzes the desaturation (aromatization) of the ring A of C19 androgens and converts them to C18 estrogens. In this process, the 19-methyl is removed. This enzyme is membrane-bound, located in the endoplasmic reticulum of estrogen-producing cells of ovaries, placenta, testes, adipose, and brain tissues. Aromatase is encoded by the CYP19 gene, and functions in complex with NADPH-FERRIHEMOPROTEIN REDUCTASE in the cytochrome P-450 system. | |
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