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Amino Acid Substitution

Amino Acid Substitutions | Substitution, Amino Acid | Substitutions, Amino Acid

The naturally occurring or experimentally induced replacement of one or more amino acids in a protein with another. If a functionally equivalent amino acid is substituted, the protein may retain wild-type activity. Substitution may also diminish or eliminate protein function. Experimentally induced substitution is often used to study enzyme activities and binding site properties.

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