Diseases and Injuries
>> Tabular
Index
>> Alphabetic
Index
Procedures
>> Tabular
Index
>>
Alphabetic Index
Appendices
>> Drugs
/ Chemicals
>> External Causes
Other Resources
>> HCPCS Alpha
>> Medical
Dictionary
>> Drug Directory
Tips
Contribute
|
|
Sirolimus
Rapamycin | AY 22-989 | Rapamune | AY 22 989 | AY 22989
A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties. |
| |
|
The National Library of Medicine (terms and conditions) |
|