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Receptors, GABA

GABA Receptors | Receptors, gamma-Aminobutyric Acid | gamma-Aminobutyric Acid Receptors | GABA Receptor | gamma-Aminobutyric Acid Receptor | Receptor, GABA | Receptor, gamma-Aminobutyric Acid | Receptors, gamma Aminobutyric Acid

Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen.

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