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| Gangliosidoses Ganglioside Storage Diseases | Ganglioside Storage Disorders | Gangliosidosis | Ganglioside Storage Disease | Ganglioside Storage Disorder | Storage Disease, Ganglioside | Storage Diseases, Ganglioside | Storage Disorder, Ganglioside A group of often fatal inherited diseases marked by the accumulation of GANGLIOSIDES in LYSOSOMES secondary to enzymatic deficiency states. Gangliosidoses include TAY-SACHS DISEASE; GANGLIOSIDOSIS GM1; GANGLIOSIDOSES GM2; and SANDHOFF DISEASE; which share the infantile or childhood onset of CENTRAL NERVOUS SYSTEM deterioration. (Menkes, Textbook of Child Neurology, 5th ed, pp89-97) | |
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