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| Similar words: Freund's Adjuvant | |
| Freund's Adjuvant Freund Adjuvant | Adjuvant, Freund | Adjuvant, Freund' | s | Freunds Adjuvant An antigen solution emulsified in mineral oil. The complete form is made up of killed, dried mycobacteria, usually M. tuberculosis, suspended in the oil phase. It is effective in stimulating cell-mediated immunity (IMMUNITY, CELLULAR) and potentiates the production of certain IMMUNOGLOBULINS in some animals. The incomplete form does not contain mycobacteria. | |
| Adjuvants, Immunologic Immunoactivators | Immunoadjuvants | Immunomodulators | Immunopotentiators | Immunostimulants | Adjuvant, Immunologic | Adjuvants, Immunological | Immunologic Adjuvants | Immunological Adjuvant | Adjuvant, Immunological | Immunologic Adjuvant Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity. | |
| Radiotherapy, Adjuvant Adjuvant Radiotherapy | Adjuvant Radiotherapies | Radiotherapies, Adjuvant Radiotherapy given to augment some other form of treatment such as surgery or chemotherapy. Adjuvant radiotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment. | |
| Chemotherapy, Adjuvant Drug Therapy, Adjuvant | Adjuvant Drug Therapy | Adjuvant Chemotherapy Drug therapy given to augment or stimulate some other form of treatment such as surgery or radiation therapy. Adjuvant chemotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment. | |
| Adjuvants, Pharmaceutic Adjuvant, Pharmaceutic | Adjuvant, Pharmaceutical | Adjuvants, Pharmaceutical | Pharmaceutic Adjuvant | Pharmaceutic Adjuvants | Pharmaceutical Adjuvant | Pharmaceutical Adjuvants Agents that aid or increase the action of the principle drug or that affect the absorption, mechanism of action, metabolism, or excretion of the primary drug in such a way as to enhance its effects. | |
| Arthritis, Experimental Adjuvant Arthritis | Arthritis, Adjuvant-Induced | Arthritis, Collagen-Induced | Arthritis, Adjuvant | Collagen Arthritis | Arthritides, Collagen | Arthritis, Collagen | Collagen Arthritides | Collagen-Induced Arthritides ARTHRITIS that is induced in experimental animals. Immunological methods and infectious agents can be used to develop experimental arthritis models. These methods include injections of stimulators of the immune response, such as an adjuvant (ADJUVANTS, IMMUNOLOGIC) or COLLAGEN. | |
| Encephalomyelitis, Experimental Autoimmune Autoimmune Encephalomyelitis, Experimental | Encephalomyelitis, Allergic | Encephalomyelitis, Autoimmune, Experimental | Allergic Encephalomyelitis | Allergic Encephalomyelitis, Experimental | Autoimmune Experimental Encephalomyelitis An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5) | |
| Cell Wall Skeleton A mucoprotein found in the cell wall of various types of bacteria. It has adjuvant and antitumor activities and has been used to augment the production of lymphokine-activated killer (LAK) cells. | |
| Gelatin Gelafusal A product formed from skin, white connective tissue, or bone COLLAGEN. It is used as a protein food adjuvant, plasma substitute, hemostatic, suspending agent in pharmaceutical preparations, and in the manufacturing of capsules and suppositories. | |
| Oxazolone 2-Phenyl-4-(ethoxymethylene)oxazol-5-one | 4-Ethoxymethylene-2-phenyloxazolone | 4 Ethoxymethylene 2 phenyloxazolone Immunologic adjuvant and sensitizing agent. | |
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