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Anti-Arrhythmia Agents

Antifibrillatory Agents | Cardiac Depressants | Myocardial Depressants | Anti-Arrhythmia Drugs | Anti-Arrhythmics | Antiarrhythmia Agents | Antiarrhythmia Drugs | Antiarrhythmic Drugs | Agents, Anti-Arrhythmia | Agents, Antiarrhythmia

Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.

Flecainide

Flecainide Acetate | Flecainide Monoacetate | Flecainide Monoacetate, (+-)-Isomer | Flecainide Monoacetate, (R)-Isomer | Flecainide Monoacetate, (S)-Isomer | Flecainide, (R)-Isomer | Flecainide, (S)-Isomer | R818 | Tambocor

A potent anti-arrhythmia agent, effective in a wide range of ventricular and atrial arrhythmias and tachycardias. Paradoxically, however, in myocardial infarct patients with either symptomatic or asymptomatic arrhythmia, flecainide exacerbates the arrhythmia and is not recommended for use in these patients.

Verapamil

Iproveratril | Calan | Cordilox | Dexverapamil | Falicard | Finoptin | Isoptin | Isoptine | Izoptin

A calcium channel blocker that is a class IV anti-arrhythmia agent.

Carteolol

Carteolol Hydrochloride | Carteolol Monohydrochloride | OPC-1085 | Hydrochloride, Carteolol | Monohydrochloride, Carteolol | OPC 1085 | OPC1085

A beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.

Bepridil

1978-CERM | Bepadin | Bepridil Monohydrochloride | Bepridil Monohydrochloride, Monohydrate | Bepridil Monohydrochloride, alpha-Isomer | Bepridil, (+)-Isomer | Bepridil, (+-)-Isomer | Bepridil, (-)-Isomer | Bepridil, alpha-Isomer | CERM-1978

A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist.

Digitalis Glycosides

Glycosides, Digitalis

Glycosides from plants of the genus DIGITALIS. Some of these are useful as cardiotonic and anti-arrhythmia agents. Included also are semi-synthetic derivatives of the naturally occurring glycosides. The term has sometimes been used more broadly to include all CARDIAC GLYCOSIDES, but here is restricted to those related to Digitalis.

Anti-Glomerular Basement Membrane Disease

Anti-GBM Disease | Anti GBM Disease | Anti Glomerular Basement Membrane Disease | Anti-GBM Diseases | Disease, Anti-GBM | Diseases, Anti-GBM

Glomerulonephritis, usually of a generalized proliferative crescent-forming histologic type with a rapidly progressive course, marked by circulating anti-GBM antibodies and linear deposits of immunoglobulin and complement along the glomerular basement membrane. When associated with pulmonary hemorrhage the condition is called GOODPASTURE SYNDROME. (Dorland, 28th ed)

Prajmaline

N-Propylajmaline | Prajmalium | Neo-Gilurytmal | Prajmalium Bitartrate | Bitartrate, Prajmalium | N Propylajmaline | Neo Gilurytmal | NeoGilurytmal

A derivative of the rauwolfia alkaloid AJMALINE. It is an anti-arrhythmia agent, but may cause liver damage.

Potassium Channel Blockers

Channel Blockers, Potassium | Blockers, Potassium Channel

A class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION POTENTIALS. They are used as ANTI-ARRHYTHMIA AGENTS and VASODILATOR AGENTS.

Antibodies, Anti-Idiotypic

Anti-Antibodies | Anti-Idiotype Antibodies | Antibodies, Internal Image | Antigamma Globulin Antibodies | Antiglobulins | Anti Antibodies | Anti Idiotype Antibodies | Anti-Idiotypic Antibodies | Antibodies, Anti Idiotypic

Antibodies which react with the individual structural determinants (idiotopes) on the variable region of other antibodies.
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