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2009 ICD-9-CM

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Untranslated Regions

UTRs | Region, Untranslated | Regions, Untranslated | Untranslated Region

The parts of the messenger RNA sequence that do not code for product, i.e. the 5' UNTRANSLATED REGIONS and 3' UNTRANSLATED REGIONS.

3' Untranslated Regions

3' | UTR | 3' | UTR | 3' | Untranslated Region | 3' | UTRs | 3' | UTRs | Region, 3' | Untranslated | Regions, 3' | Untranslated | UTR, 3' | | UTRs, 3' | | Untranslated Region, 3' | | Untranslated Regions, 3' |

The sequence at the 3' end of messenger RNA that does not code for product. This region contains transcription and translation regulating sequences.

RNA, Untranslated

RNA, Noncoding | RNA, Nontranslated | Noncoding RNA | Nontranslated RNA | Untranslated RNA

RNA which does not code for protein but has some enzymatic, structural or regulatory function. Although ribosomal RNA; (RNA, RIBOSOMAL) and transfer RNA; (RNA, TRANSFER) are also untranslated they are not included here.

DNA, Intergenic

DNA, Junk | DNA, Spacer | Intergenic DNA | Junk DNA | Spacer DNA | Intercistronic Region | Intercistronic Sequence | Intergenic Region | Intergenic Sequence | Sequence, Intergenic | DNAs, Intergenic | DNAs, Junk | DNAs, Spacer | Intercistronic Regions

Any of the DNA in between gene-coding DNA, including untranslated regions, 5' and 3' flanking regions, INTRONS, non-functional pseudogenes, and non-functional repetitive sequences. This DNA may or may not encode regulatory functions.

Immunoglobulin Variable Region

Variable Region, Ig | Variable Region, Immunoglobulin | Framework Region | Immunoglobulin V | Variable Region | Framework Regions | Ig Variable Region | Ig Variable Regions | Immunoglobulin Variable Regions | Immunoglobulin Vs | Regions, Framework

That region of the immunoglobulin (antibody) molecule that varies in its amino acid sequence and composition, confers the antigenic specificity, and is thought to comprise the binding site for the antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions.

5' Untranslated Regions

5' | UTR | Leader Sequences, mRNA | Leader mRNA Sequences | mRNA Leader Sequences | 5' | UTR | 5' | UTRs | 5' | Untranslated Region | 5' | UTRs | Leader Sequence, mRNA | Leader mRNA Sequence | Region, 5' | Untranslated | UTR, 5' |

The sequence at the 5' end of the messenger RNA that does not code for product. This sequence contains the ribosome binding site and other transcription and translation regulating sequences.

Bay Region (Chemistry)

Bay Region | Bay Regions | Bay Regions (Chemistry) | Region, Bay | Region, Bay (Chemistry) | Regions, Bay | Regions, Bay (Chemistry)

An indentation of three fused benzene rings. A common bay region is the site on BENZO(A)PYRENE, an indirect carcinogen that is metabolically activated by the P-450 system at the 7,8-double bond, leading to a 7,8-oxide, which is rapidly converted to a 7,8-dihydrodiol and later epoxidated near the bay region at the 9,10-double bond. The resulting product, a diol-epoxide is a poor substrate for epoxide hydratase and is released from the mitochondria into the cell as a highly reactive electrophil, becoming an 'ultimate' carcinogen, as it reacts with negative charges in DNA. (From Segen, Dictionary of Modern Medicine, 1992)

Euchromatin

Euchromatins

Chromosome regions that are loosely packaged and more accessible to RNA polymerases than HETEROCHROMATIN. These regions also stain differentially in CHROMOSOME BANDING preparations.

Locus Control Region

Control Region, Locus | Control Regions, Locus | Locus Control Regions | Region, Locus Control | Regions, Locus Control

A regulatory region first identified in the human beta-globin locus but subsequently found in other loci. The region is believed to regulate TRANSCRIPTION by opening and remodeling CHROMATIN structure. It may also have ENHANCER activity.

Terminator Regions (Genetics)

Terminator Sequence | Transcriptional Terminator Regions | Terminator Regions | Region, Terminator | Region, Terminator (Genetics) | Region, Transcriptional Terminator | Regions, Terminator | Regions, Terminator (Genetics) | Terminator Region

DNA sequences which signal the termination of transcription.
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