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| Apolipoproteins E Apo-E | Apo E | ApoE | Apoprotein (E) | Apoproteins E Prominent protein constituents of plasma VLDL, chylomicrons, and a subfraction of HDL as well as of remnant lipoproteins which are derived from the lipoprotein lipase-mediated intravascular catabolism of triglyceride-rich lipoproteins. Apolipoproteins E are recognized by the LDL receptor and Apo E receptor. Any defect in the Apo E metabolism leads to increased plasma Apo E levels. A strong association has been found between high levels of Apo E and type III hyperlipoproteinemia. |