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| Osteogenesis Imperfecta Fragilitas Ossium | Lobstein Disease | Lobstein' | s Disease | Disease, Lobstein | Disease, Lobstein' | s | Lobsteins Disease | Ossiums, Fragilitas Autosomal dominant COLLAGEN DISEASES resulting from defective biosynthesis of COLLAGEN TYPE I and characterized by brittle, osteoporotic, and easily fractured bones. It may also present with blue sclerae, loose joints, and imperfect dentin formation. There are four major types, I-IV. |