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| Lymphocyte Activation Blast Transformation | Blastogenesis | Lymphoblast Transformation | Lymphocyte Stimulation | Lymphocyte Transformation | Transformation, Blast | Transformation, Lymphoblast | Transformation, Lymphocyte | Activation, Lymphocyte Morphologic alteration of small lymphocytes in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS, MITOGENS such as PHYTOHEMAGGLUTININS, and by specific antigens. It may also occur in vivo, as in GRAFT REJECTION and chronic myelogenous leukemia (LEUKEMIA, MYELOID, CHRONIC). |