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| Lupus Erythematosus, Systemic Libman-Sacks Disease | Lupus Erythematosus Disseminatus | Systemic Lupus Erythematosus | Disease, Libman-Sacks | Libman Sacks Disease A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. |