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| Lovastatin Mevinolin | 6-Methylcompactin | Lovastatin, (1 alpha(S*))-Isomer | Lovastatin, 1 alpha-Isomer (without R*/S* notation) | MK-803 | Mevacor | Monacolin K | 6 Methylcompactin | MK 803 | MK803 A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver. |