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| Jaundice, Chronic Idiopathic Dubin-Johnson Syndrome | Chronic Idiopathic Jaundice | Chronic Idiopathic Jaundices | Dubin Johnson Syndrome | Idiopathic Jaundice, Chronic | Idiopathic Jaundices, Chronic | Jaundices, Chronic Idiopathic | Syndrome, Dubin-Johnson A benign, autosomally recessive inherited hyperbilirubinemia characterized by the presence of a dark pigment in the centrilobular region of the liver cells. There is a functional defect in biliary excretion of bilirubin, cholephilic dyes, and porphyrins. Affected persons may be asymptomatic or have vague constitutional or gastrointestional symptoms. The liver may be slightly enlarged, and oral and intravenous cholangiography fails to visualize the biliary tract. |