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| Immune Tolerance Immunosuppression (Physiology) | Immunosuppressions (Physiology) | Tolerance, Immune The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc. |