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| Histidine Decarboxylase Histidine Carboxy-Lyase | Carboxy-Lyase, Histidine | Decarboxylase, Histidine | Histidine Carboxy Lyase An enzyme that catalyzes the decarboxylation of histidine to histamine and carbon dioxide. It requires pyridoxal phosphate in animal tissues, but not in microorganisms. EC 4.1.1.22. |