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Factor XII

Coagulation Factor XII | Hageman Factor | Blood Coagulation FactorXI | Coagulation FactorXI, Blood | Factor XII, Coagulation | FactorXI, Blood Coagulation | XII, Coagulation Factor

Stable blood coagulation factor activated by contact with the subendothelial surface of an injured vessel. Along with prekallikrein, it serves as the contact factor that initiates the intrinsic pathway of blood coagulation. Kallikrein activates factor XII to XIIa. Deficiency of factor XII, also called the Hageman trait, leads to increased incidence of thromboembolic disease.
 
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