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| Dystonia Musculorum Deformans Childhood Torsion Disease | Idiopathic Torsion Dystonia | Oppenheim-Ziehen Disease | Progressive Torsion Spasm | Torsion Dystonia | Dystonia Deformans Musculorum | Dystonia Deformans Progressiva | Torsion Disease of Childhood A condition characterized by focal DYSTONIA that progresses to involuntary spasmodic contractions of the muscles of the legs, trunk, arms, and face. The hands are often spared, however, sustained axial and limb contractions may lead to a state where the body is grossly contorted. Onset is usually in the first or second decade. Familial patterns of inheritance, primarily autosomal dominant with incomplete pentrance, have been identified. (Adams et al., Principles of Neurology, 6th ed, p1078) |