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| Microbial Collagenase Clostridiopeptidase A | Clostridium histolyticum Collagenase | Collagenase, Microbial | Collagenase-Like Peptidase | Collalysine | Nucleolysin | Collagenase Like Peptidase | Collagenase, Clostridium histolyticum | Peptidase, Collagenase-Like A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3. |