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Ribosomal Protein S6 Kinases, 70kD

p70 S6 Kinase | p70s6k | S6 Kinase, p70

A family of ribosomal protein S6 kinases that are considered the major physiological kinases for RIBOSOMAL PROTEIN S6. Unlike RIBOSOMAL PROTEIN S6 KINASES, 90KD the proteins in this family are sensitive to the inhibitory effects of RAPAMYCIN and contain a single kinase domain. They are referred to as 70kD proteins, however ALTERNATIVE SPLICING of mRNAs for proteins in this class also results in 85kD variants being formed.
 
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