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| RNA 5' Terminal Oligopyrimidine Sequence 5' | TOP Messenger RNA | 5' | TOP Sequence | 5' | TOP mRNA | RNA 5' | Terminal Oligopyrimidine Regulatory Sequence | 5' | TOP Sequences | Sequence, 5' | TOP | Sequences, 5' | TOP A regulatory sequence found in the 5' terminal regions of a variety of RNA species. The sequence starts with a CYTIDINE, which is followed by a stretch of 5 to 15 PYRIMIDINE NUCLEOTIDES. Messenger RNA that contains the 5' Terminal OligoPyrimidine tract is often referred to as 5' TOP mRNA. The sequence acts as a translational regulator and has been found in mRNAs for PEPTIDE ELONGATION FACTORS and RIBOSOMAL PROTEINS. |