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Receptor, EphA1

EphA1 Receptor | EPHA1 Protein | EPHA1 Receptor Tyrosine Kinase | Eph Receptor | Esk Gene Product | Esk Protein

The founding member of the Eph family receptors. It was first cloned from an erythropoietin-producing human hepatocellular carcinoma cell line and is highly conserved among many mammalian species. Overproduction of the EphA1 receptor is associated with tumors and tumor cells of epithelial origin. It is also expressed at high levels in LIVER, LUNG and KIDNEY, which is in contrast to many other members of the Eph receptor that are found primarily in tissues of the nervous system.
 
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