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| DNA Topoisomerase IV parC Protein | parE Protein | Topo IV | Topoisomerase IV | Topoisomerase IV Subunit A | Topoisomerase IV Subunit B | parC Gene Product | parC Gene Product, Topo IV | parE Gene Product | parE Gene Product, Topo IV | Topoisomerase IV, DNA A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Topoisomerase IV binds to DNA as a heterotetramer consisting 2 parC and 2 parE subunits. Topoisomerase IV is a decatenating enzyme that resolves interlinked daughter chromosomes following DNA replication. |