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DNA Gyrase

DNA Gyrase A Subunit | DNA Gyrase B Subunit | gyrA Protein | gyrB Protein | DNA-Gyrase | gyrA Gene product | gyrB Gene Product

A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Gyrase binds to DNA as a heterotetramer consisting two A and two B subunits. In the presence of ATP, gyrase is able to convert relaxed circular DNA duplex into a superhelix. In the absence of ATP, supercoiled DNA is relaxed by DNA gyrase.
 
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