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| P-Glycoprotein MDR1 Protein | Multidrug Resistance Protein 1 | ATP-Binding Cassette, Sub-Family B, Member 1 | P-gp | PGY-1 Protein | P Glycoprotein | PGY 1 Protein A 170 kD transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE). |