Free online searchable
2009 ICD-9-CM
Diseases and Injuries
>> Tabular
Index
>> Alphabetic
Index
Procedures
>> Tabular
Index
>>
Alphabetic Index
Appendices
>> Drugs
/ Chemicals
>> External Causes
Other Resources
>> HCPCS Alpha
>> Medical
Dictionary
>> Drug Directory
Tips
Contribute
| Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Laser Desorption-Ionization Mass Spectrometry, Matrix-Assisted | MALD-MS | MALDI | Mass Spectrometry, Matrix-Assisted Laser Desorption-Ionization | Mass Spectroscopy, Matrix-Assisted Laser Desorption-Ionization | MALDI-MS | MS-MALD | MALDI MS A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample-matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced, and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis. |