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| Receptor, erbB-2 HER-2 Proto-Oncogene Protein | Proto-Oncogene Protein HER-2 | Proto-Oncogene Protein p185(neu) | Receptor, neu | c-erbB-2 Protein | erbB-2 Proto-Oncogene Protein | erbB-2 Receptor Protein-Tyrosine Kinase | neu Proto-Oncogene Protein A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number of adenocarcinomas. It has extensive homology to and can heterodimerize with the EGF receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR), the erbB-3 receptor (RECEPTOR, ERBB-3) and the erbB-4 receptor. Activation of the erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB receptor family members. |