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Aflatoxin B1
Aflatoxin B | Aflatoxin B1 Dihydrochloride, (6aR-cis)-Isomer | Aflatoxin B1, (6aR-cis)-Isomer, 14C-Labeled | Aflatoxin B1, (6aR-cis)-Isomer, 2H-Labeled | Aflatoxin B1, (6aR-cis)-Isomer, 3H-Labeled | Aflatoxin B1, cis(+,-)-Isomer | HSDB-3453
A potent hepatotoxic and hepatocarcinogenic mycotoxin produced by the Aspergillus flavus group of fungi. It is also mutagenic, teratogenic, and causes immunosuppression in animals. It is found as a contaminant in peanuts, cottonseed meal, corn, and other grains. The mycotoxin requires epoxidation to aflatoxin B1 2,3-oxide for activation. Microsomal monooxygenases biotransform the toxin to the less toxic metabolites aflatoxin M1 and Q1. |
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