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| Oncogene Protein gp140(v-fms) fms Oncogene Protein gp120 | fms Oncogene Protein gp140 | gp120(v-fms) | gp140(v-fms) | v-fms Protein | fms Oncogene Product gp120 | fms Oncogene Product gp140 | gp120 v-fms | gp140 v-fms | gp120 v fms | gp140 v fms | v fms Protein | v-fms, gp120 Transforming glycoprotein coded by the fms oncogene from the Susan McDonough strain of feline sarcoma virus (SM-FeSV). The oncogene protein v-fms lacks sequences, which, in the highly homologous proto-oncogene protein c-fms (CSF-1 receptor), normally serve to regulate its tyrosine kinase activity. The missing sequences in v-fms mimic the effect of ligand and lead to constitutive cell growth. The protein gp120(v-fms) is post-translationally modified to generate gp140(v-fms). |