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| von Willebrand Factor Factor VIII-Related Antigen | F VIII-vWf | Factor VIIIR-Ag | Factor VIIIR-RCo | Plasma Factor VIII Complex | Ristocetin Cofactor | Ristocetin-Willebrand Factor | vWF Ag | von Willebrand Factor Type IIB | von Willebrand Protein | Ag, vWF | F VIII vWf A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in von Willebrand's disease is due to the deficiency of this factor. |