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| Smallpox Alastrim | Variola | Variola Minor | Minor, Variola | Minors, Variola | Variola Minors | Variolas An acute, highly contagious, often fatal infectious disease caused by an orthopoxvirus characterized by a biphasic febrile course and distinctive progressive skin eruptions. Vaccination has succeeded in eradicating smallpox worldwide. (Dorland, 28th ed) |