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| Receptor, Epidermal Growth Factor EGF Receptor | Epidermal Growth Factor Receptor | Epidermal Growth Factor Receptor Protein-Tyrosine Kinase | Receptor, EGF | Receptor, TGF-alpha | Receptor, Transforming-Growth Factor alpha | Receptor, Urogastrone | TGF-alpha Receptor A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF related peptides including TRANSFORMING GROWTH FACTOR ALPHA, amphiregulin, and heparin-binding EGF-like growth factor. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell. |